Revitalift Derm Intensives Night Serum with 0.3% Pure Retinol is our most potent and has our highest concentration of Pure Retinol. So effective, in a clinical study, 100% of women showed reduction in wrinkles, even deep ones. Pure Retinol is a top dermatologist recommended anti-aging ingredient proven to fight key signs of aging such as wrinkles, even deep ones. With many retinols available in skincare, look for those that say PURE.